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Personalized Medicine in the Era of Genomics

Personalized Medicine in the Era of Genomics
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Author(s): Navneet Kaur Soni (Delhi Technological University, India), Nitin Thukral (Delhi Technological University, India)and Yasha Hasija (Delhi Technological University, India)
Copyright: 2016
Pages: 32
Source title: Handbook of Research on Computational Intelligence Applications in Bioinformatics
Source Author(s)/Editor(s): Sujata Dash (North Orissa University, India)and Bidyadhar Subudhi (National Institute of Technology, India)
DOI: 10.4018/978-1-5225-0427-6.ch014

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Abstract

Personalized medicine is a model that aims at customizing healthcare and tailoring medicine according to an individual`s genetic makeup. It classifies individuals that differ in their susceptibility to a particular disease or response to a particular treatment into subpopulations based on individual's unique genetic and clinical information along with environmental factors. The completion of Human Genome Project and the advent of high-throughput genome analysis tools has helped in building and strengthening this model. There lies a huge potential in the implementation of personalized medicine to significantly improve the clinical outcomes; however, its implementation into clinical practice remains slow and is a matter of concern. This chapter aims at acquainting readers with the underlying concepts and components of personalized medicine supplemented with some disease-based case studies, discussing challenges and recent advancements in the implementation of the model of personalized medicine.

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