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Exploring Novel Strategies for Lipid-Based Drug Delivery
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Author(s): Sabna Kotta (Buraidah Private Colleges (BPC) - Qassim, Saudi Arabia), Navneet Sharma (Indian Institute of Technology Delhi, HauzKhas, New Delhi, India), Prateek Raturi (Institute of Nuclear Medicine and Allied Sciences, New Delhi, India), Mohd Aleem (Institute of Nuclear Medicine and Allied Sciences, New Delhi, India)and Rakesh Kumar Sharma (Defence Food Research Laboratory, Karnataka, India)
Copyright: 2018
Volume: 3
Issue: 1
Pages: 22
Source title:
Journal of Nanotoxicology and Nanomedicine (JNN)
Editor(s)-in-Chief: Bakhtiyor Rasulev (North Dakota State University, USA)
DOI: 10.4018/JNN.2018010101
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Abstract
Currently, the concept of lipid-based drug delivery systems has gained much interest because of their capability to deliver drugs which dissolve sparingly in water or insoluble in nature. Several methods of lipid-based drug delivery exist, and each method has its own advantages as well as limitations. The primary objective of the formulation development is to improve the bioavailability of the drug. The nano-sized lipid-based drug delivery systems have enough potential to do so. This article addresses the various barriers to the transportation of drugs through certain routes and also the common excipients which used to develop the lipid-based drug delivery systems. It provides a thorough overview of the lipid formulation classification scheme (LFCS) and also deals with several formulation & evaluation aspects of lipid-based drug delivery system. Further, it focuses on the formulations which are already available in the market and their regulatory concerns, respectively.
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