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Nanomaterials to Overcome Emergence and Re-Emergence of Superbugs: Nanoarsenals for Superbugs
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Author(s): Manju Nagpal (Chitkara University, India), Malkiet Kaur (Chitkara University, India), Manjinder Singh (Chitkara University, India)and Geeta Aggarwal (Delhi Pharmaceutical Sciences and Research University (DPSRU), India)
Copyright: 2021
Pages: 42
Source title:
Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities
Source Author(s)/Editor(s): Dimple Sethi Chopra (Punjabi University, India)and Ankur Kaul (Institute of Nuclear Medicine and Allied Sciences, India)
DOI: 10.4018/978-1-7998-0307-2.ch010
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Abstract
Antimicrobial resistance remains a substantial global health concern, invigorating the critical need for alternate therapeutic options to combat chronic intracellular infections and biofilms so as to shorten the hospital stays, and hence mortality. Nanomaterials have been developed as delivery carriers for antibiotics to improve their penetration through these biofilms. Nanoformulations of existing antibiotics has led to enhanced bioavailability and site specificity. Moreover, diagnosis of infections using efficient nanosensors or probes may speed up the treatment process at earlier stages of infection.
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