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Personalized Approach in Nanomedicine: Understanding Adverse Effects and Their Risk Assessment

Personalized Approach in Nanomedicine: Understanding Adverse Effects and Their Risk Assessment
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Author(s): Maria Vlasova (University of Eastern Finland, Finland) and Boris V. Smirin (University of Eastern Finland, Finland)
Copyright: 2017
Pages: 21
Source title: Recent Advances in Drug Delivery Technology
Source Author(s)/Editor(s): Raj K. Keservani (Rajiv Gandhi Proudyogiki Vishwavidyalaya, India), Anil K. Sharma (GD Goenka University, India) and Rajesh Kumar Kesharwani (National Institute of Technology, Warangal, India)
DOI: 10.4018/978-1-5225-0754-3.ch001

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Abstract

This chapter characterizes need for new patient-specific approaches in medicine. The authors here illustrate role of nanomedicine and particularly nanotheranostics, combining diagnostic and therapeutic functions, in the paradigm of personalized disease treatment. This chapter discusses current insights regarding the mechanisms of nano-bio interactions and the origin of adverse effects of nanoformulations. Furthermore, this chapter illustrates possible reasons behind an individual physiological response to a given nanomedicine, such as type and stage of disease, physiological conditions and lifestyle of a patient. Finally, a review of possible approaches for the initial choice of nanoformulation, suitable for a given patient is provided at the end of the chapter.

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