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Nanomedicine as a Newly Emerging Approach Against Multidrug-Resistant Tuberculosis (MDR-TB)
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Author(s): Muthupandian Saravanan (Mekelle University, Ethiopia & Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), India), Kebret Duche (Mekelle University, Ethiopia), Tsehaye Asmelash (Mekelle University, Ethiopia), Araya Gebreyesus (Mekelle University, Ethiopia), Anima Nanda (Sathyabama University, India)and Selvaraj Arokiyaraj (Seoul National University, South Korea)
Copyright: 2017
Pages: 24
Source title:
Integrating Biologically-Inspired Nanotechnology into Medical Practice
Source Author(s)/Editor(s): B.K. Nayak (K.M. Centre for Post Graduate Studies, India), Anima Nanda (Sathyabama University, India)and M. Amin Bhat (Sathyabama University, India)
DOI: 10.4018/978-1-5225-0610-2.ch003
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Abstract
Emergence of MDR-TB is highly associated with morbidity and mortality and it needs high concerns about the possibility of a future TB epidemic as limited therapeutic options are available. The current treatment against TB needs daily administration for at least 6 months. That in turn leads to the development and spread of drug-resistant TB. Plenty of work has been done in nanomedicine that provides hope to encounter TB effectively. In the developing world the development of nanoparticle-based aerosol vaccines for tuberculosis has potential applications using on a large scale at relatively low cost, and particularly attractive for use. This book review examines the current TB diagnostic assays and treatment by nanotechnologies and highlight recent advances in Anti-TB Drug (ATD) delivery systems and anti-TB drug encapsulation. It also discusses the impact of the nanoparticles as an emerging treatment against MDR-TB and discusses the current knowledge and potential nanomedicine to improve MDR-TB therapy.
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