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Prediction of Structural and Functional Aspects of Protein: In-Silico Approach

Prediction of Structural and Functional Aspects of Protein: In-Silico Approach
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Author(s): Arun G. Ingale (North Maharashtra University, India)
Copyright: 2014
Pages: 17
Source title: Advances in Secure Computing, Internet Services, and Applications
Source Author(s)/Editor(s): B.K. Tripathy (VIT University, India)and D. P. Acharjya (VIT University, India)
DOI: 10.4018/978-1-4666-4940-8.ch016

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Abstract

To predict the structure of protein from a primary amino acid sequence is computationally difficult. An investigation of the methods and algorithms used to predict protein structure and a thorough knowledge of the function and structure of proteins are critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this chapter sheds light on the methods used for protein structure prediction. This chapter covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, it presents an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction, giving unique insight into the future applications of the modeled protein structures. In this chapter, current protein structure prediction methods are reviewed for a milieu on structure prediction, the prediction of structural fundamentals, tertiary structure prediction, and functional imminent. The basic ideas and advances of these directions are discussed in detail.

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