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Reconfiguring Responsibility in International Clinical Trials: A Multicultural Approach
Abstract
This chapter aims to prominently position the African philosophical notion of the self within the clinical trials context (and the larger bioethics project). As opposed to autonomy-based principlism, this other-regarding or communalist perspective is proposed as the preferred alternative model. The intent is to draw further attention to the inadequacy of the principlist approach particularly in multicultural settings. It also engenders a rethink, stimulates interest, and re-assesses the failed assumptions of universal ethical principles. As a novel attempt that runs against much of the prevailing (Euro-American) intellectual mood, this approach strives to introduce the African view point by making explicit the import of the self in a re-contextualized (nay, globalized) arena. Viewed as such, research ethics is guided to go beyond autonomy-based considerations for the individual with absolute right to self-determination; to embrace more holistic-based approach, recognizing that the individual is embedded in his/her family, community, and the environment.
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