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Early-Stage Cervical Cancer: Is There a Place for Conservative Treatment?
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Author(s): Maria Luisa Fais (Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Italy), Giorgio Candotti (IRCCS San Raffaele Scientific Institute, Milan, Italy), Giulia Carboni (Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Italy), Speranza Luisa Anedda (Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Italy), Valerio Mais (Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Italy), Stefano Angioni (Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Italy)and Michele Peiretti (Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Italy)
Copyright: 2021
Pages: 19
Source title:
Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice
Source Author(s)/Editor(s): Konstantinos Dinas (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Stamatios Petousis (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Matthias Kalder (Department of Obstetrics and Gynaecology, Philipps-University of Marburg, Germany)and George Mavromatidis (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece)
DOI: 10.4018/978-1-7998-4213-2.ch011
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Abstract
Recent advances in screening and early diagnosis have decreased cervical cancer incidence and mortality rate in high-resource settings. The postponement of childbearing and the young age of women at diagnosis produced new challenges in the management of this disease. In recent years, attention has been directed to assessing more conservative procedures that can reduce treatment-related morbidity, without compromising oncologic safety and reproductive potential. Fertility sparing surgery (FSS) procedures, including cervical conization, simple or radical trachelectomy with pelvic nodes dissection or sentinel lymph node assessment, and neoadjuvant chemotherapy followed by conization, have shown encouraging results. In this chapter, the authors discuss the role of conservative surgery in the management of early-stage cervical cancer focusing on obstetrical and oncological outcomes.
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