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Monocytes as Targets for Cancer Therapies
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Author(s): Astha Singh (National Institute of Pathology, New Delhi, India)
Copyright: 2021
Pages: 7
Source title:
Handbook of Research on Advancements in Cancer Therapeutics
Source Author(s)/Editor(s): Sumit Kumar (National Institute of Pathology, New Delhi, India), Moshahid Alam Rizvi (Jamia Millia Islamia, India) and Saurabh Verma (National Institute of Pathology, India)
DOI: 10.4018/978-1-7998-6530-8.ch027
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Abstract
The importance of monocytes in modulating the lymphocyte dependent tumor necrosis is a target for cancer therapeutics. Monocytes produce a plethora of chemokine receptors. Lymphocyte to monocyte ratio is one of the negative factors in cancer patients. It is being targeted for treatment of abnormal lymphocytopenia and monocytosis in untreatable metastatic cancer patients. The aim of the chapter is to throw light on the circadian and psychological factors that modulate the progression of cancer and identify novel targets for controlling transformation of preneoplasms to neoplasms, invasiveness, and metastasis.
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