Morphologic Abnormalities of Bone Marrow Elements

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Copyright: 2024
Pages: 34
Source title: Principles and Approaches to Diagnostic Bone Marrow Examination
Source Author(s)/Editor(s): Samia Hassan Rizk (Cairo University, Egypt)
DOI: 10.4018/978-1-6684-5818-1.ch004

Keywords: Medical Diagnosis and Practice / Medical Information Science Reference / Medical Treatment & Care / Medicine & Healthcare

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Abstract

The diagnostic pathway starts with a thorough morphologic examination that should systematically evaluate every element of the bone marrow, make a differential count on smears and meticulously find and describe any abnormality. The information obtained will direct other diagnostic tracks. During this preliminary evaluation, any physiological factors should be considered, such as age. An anomaly of any marrow elements should raise an inquiry of its probable etiologies, not ignoring rare causes. A disease-specific abnormality should alert the search for other disease criteria and possible alternatives. An adequate experience with the pathology of hemopoietic disorders is necessary to anticipate their effects and search for any hidden diagnostic evidence. Careful attention to artifacts that could confuse morphologic interpretation and may lead to serious misdiagnosis is a critical consideration. This chapter discusses the typical abnormalities of bone marrow elements with some illustrations and possible etiologies.

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Morphologic Abnormalities of Bone Marrow Elements

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