The IRMA Community
Newsletters
Research IRM
Click a keyword to search titles using our InfoSci-OnDemand powered search:
|
Probiotics, Gut Microbiota, and Epigenomics: A Review of Pre-Clinical and Clinical Investigations
Abstract
Probiotics therapy has emerged as a popular, potential alternative therapy utilized in combating disorders associated with mammalian gut and visceral organs. Ongoing research suggests that probiotics directly or indirectly modulate host epigenomic signatures that in turn affect the host functional outcome. Data obtained from experimental studies indicate that microbiota, diet, and pharmaceuticals affect host epigenetic machinery subsequently resulting in specific physiological responses. Thus, molecular designing of epigenetic-based therapeutic agents may provide a valid pathway to rectifying aberrant changes and managing disease risk and progression. Recent investigations show that probiotic intervention mitigates uncharacteristic epigenetic changes that are associated with many health complications. However, stakeholders need to recognize that probiotic research is an emerging field; therefore, this science must undergo extensive mechanistic investigation. This chapter highlights the potential probiotic mediated host epigenomic interventions in disease therapy and management.
Related Content
|
Genevieve Z. Steiner-Lim, Madilyn Coles, Kayla Jaye, Najwa-Joelle Metri, Ali S. Butt, Katerina Christofides, Jackson McPartland, Zainab Al-Modhefer, Diana Karamacoska, Ethan Russo, Tim Karl.
© 2023.
47 pages.
|
|
Mohd Kashif, Mohammad Waseem, Poornima D. Vijendra, Ashok Kumar Pandurangan.
© 2023.
28 pages.
|
|
Courtney R. Acker, Rana R. Zeine.
© 2023.
27 pages.
|
|
Mahesh Pattabhiramaiah, Shanthala Mallikarjunaiah.
© 2023.
16 pages.
|
|
Dhairavi Shah, Dhaara Shah, Yara Mohamed, Danna Rosas, Alyssa Moffitt, Theresa Hearn Haynes, Francis Cortes, Taunjah Bell Neasman, Phani kumar Kathari, Ana Villagran, Rana R. Zeine.
© 2023.
28 pages.
|
|
Mohammad Uzair, Hammad Qaiser, Muhammad Arshad, Aneesa Zafar, Shahid Bashir.
© 2023.
23 pages.
|
|
Akila Muthuramalingam, Ashok Kumar Pandurangan, Subhamoy Banerjee.
© 2023.
17 pages.
|
|
|