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Robust Blood-Glucose Control of Type I Diabetes Patients Under Intensive Care Using Mathematica
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Author(s): Béla Paláncz (Budapest University of Technology and Economics, Hungary), Levente Kovács (Budapest University of Technology and Economics, Hungary), Balázs Benyó (Budapest University of Technology and Economics, Hungary)and Zoltán Benyó (Budapest University of Technology and Economics, Hungary)
Copyright: 2008
Pages: 10
Source title:
Encyclopedia of Healthcare Information Systems
Source Author(s)/Editor(s): Nilmini Wickramasinghe (Illinois Institute of Technology, USA)and Eliezer Geisler (Illinois Institute of Technology, USA)
DOI: 10.4018/978-1-59904-889-5.ch151
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Abstract
This article presents a robust control design method on frequency domain using Mathematica for regularization of glucose level in Type I diabetes persons under intensive care. The method originally proposed under Mathematica by Helton and Merino (1998) is now improved with a disturbance rejection constraint inequality, and is tested on the three-state minimal model. Nonlinear closed loop simulation in state-space, in case of standard meal disturbances, demonstrates the robustness of the resulted high-order linear controller. The obtained results are compared with H8 design implemented with Matlab, proving that the controller (for the considered model parameters) can operate properly, even in case of parameter values of the worst-case scenario.
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