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Uterine Leiomyoma or Sarcoma?: What Should I Do?

Uterine Leiomyoma or Sarcoma?: What Should I Do?
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Author(s): Theodoros Theodoridis (1st Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Dimitra Aivazi (1st Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Leonidas Zepiridis (1st Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece)and Nikolaos Vlachos (1st Department of Obstetrics and Gynaecology, National Kapodestrian University, Athens, Greece)
Copyright: 2021
Pages: 16
Source title: Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice
Source Author(s)/Editor(s): Konstantinos Dinas (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Stamatios Petousis (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece), Matthias Kalder (Department of Obstetrics and Gynaecology, Philipps-University of Marburg, Germany)and George Mavromatidis (2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece)
DOI: 10.4018/978-1-7998-4213-2.ch020

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Abstract

Uterine leiomyomas are benign neoplasms derived from the smooth muscle cells of the myometrium. In contrast, uterine sarcomas are rare tumors, with a prevalence of 3-7 per 100,000 women, originating from myometrial cells or endometrial connective tissue. Uterine sarcomas and especially leiomyosarcomas are more aggressive than uterine epithelial neoplasms. The differential diagnosis between leiomyoma and uterine sarcoma preoperatively remains challenging for the clinical practitioner in order to determine optimal treatment. The chapter aims to summarize current evidence regarding differential diagnosis and optimal management of these two challenging clinical entities.

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