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Automatic Computerized Diagnostic Tool for Down Syndrome Detection in Fetus

Automatic Computerized Diagnostic Tool for Down Syndrome Detection in Fetus
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Author(s): Michael Dinesh Simon (Anna University, India) and Kavitha A. R. (Anna University, India)
Copyright: 2019
Pages: 18
Source title: Histopathological Image Analysis in Medical Decision Making
Source Author(s)/Editor(s): Nilanjan Dey (Techno India College of Technology, India), Amira S. Ashour (Tanta University, Egypt), Harihar Kalia (Seemantha Engineering College, India), R.T. Goswami (Techno India College of Technology, India) and Himansu Das (KIIT University, India)
DOI: 10.4018/978-1-5225-6316-7.ch010

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Abstract

Down syndrome is a genetic disorder and the chromosome abnormality observed in humans that can cause physical and mental abnormalities. It can never be cured or rectified. Instead it has to be identified in the fetus and prevented from being born. Many ultrasonographic markers like nuchal fold, nasal bone hypoplasia, femur length, and EIF are considered to be the symptoms of Down syndrome in the fetus. This chapter deals with the creation of automatic and computerized diagnostic tool for Down syndrome detection based on EIF. The proposed system consists of two phases: 1) training phase and 2) testing phase. In training phase, the fetal images with EIF and Down syndrome is analyzed and characteristics of EIF are collected. In testing phase, detection of Down syndrome is performed on the fetal image with EIF based on the knowledge cluster obtained using ESOM. The performance of the proposed system is analyzed in terms of sensitivity, accuracy, and specificity.

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