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Investigation of Potential Neuroprotective Role of Chitosan-Based Biomaterials and Their Derivatives by Targeting Glial Cells
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Author(s): Youssef Ait Hamdan (University of Rennes, France & Higher Normal School, Cadi Ayyad University, Morocco), Mohammed Rhazi (Higher Normal School, Cadi Ayyad University, Morocco), Hamid Kabdy (Faculty of Sciences, Cadi Ayyad University, Morocco), Abdelali Benmaloui (Faculty of Sciences Semlalia, Morocco), Samia Elouali (Higher Normal School, Cadi Ayyad University, Morocco), Jawad Laadraoui (Faculty of Sciences, Hassan II University, Morocco), Zainab Haidar Ahmad (University of Rennes, France), Nadia Eladlani (Higher Normal school, Cadi Ayyad University, Morocco)and Hassane Oudadesse (University of Rennes, France)
Copyright: 2024
Pages: 25
Source title:
Physiology and Function of Glial Cells in Health and Disease
Source Author(s)/Editor(s): Bilal El-Mansoury (Faculty of Sciences, Chouaib Doukkali University, Morocco), Omar El Hiba (Chouaib Doukkali University, Morocco)and Arumugam Radhakrishnan Jayakumar (University of Miami, USA)
DOI: 10.4018/978-1-6684-9675-6.ch019
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Abstract
Glial cells, although often overlooked in comparison with neurons, play a crucial role in the structure and function of the nervous system. Their loss can lead to impairment of functions such as learning and memory, contributing to neurodegenerative diseases. To combat these diseases effectively, therapeutic strategies must restore the function of neuronal and glial cells. Natural resources offer promising therapeutic molecules for the treatment of neurodegenerative diseases. Chitosan (CTS), chitooligosaccharide (COS) and their derivatives from arthropod exoskeletons have attracted the attention of neuroscientists because of their neuroprotective effects and their ability to transport therapeutic substances across the blood-brain barrier (BBB). This chapter explores the role of natural resources in the fight against neuronal diseases.
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